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The standard risk among females aged 50-59 is approximately 27 cases per 10,000 women each year. The upsurge in risk is apparently connected with duration of treatment, with the boost becoming obvious after treatment for four years in a single major study. The just main randomised trial of oestrogen-just therapy showed no upsurge in risk of breast tumor after almost seven years in hysterectomised females. Professionals concluded that there is insufficient proof on the consequences of hormone therapy on cardiovascular disease in the first post-menopausal years. They stated hormone therapy shouldn’t be utilized for treatment or avoidance of heart disease.